Varus knee osteoarthritis: Elevated synovial CD15 counts correlate with inferior biomechanical properties of lateral-compartment cartilage

Cartilage Degeneration and Alignment in Severe Varus Knee Osteoarthritis

OBJECTIVES The aim of this study was to examine the relationship between cartilage, ligament, and meniscus degeneration and radiographic alignment in severe varus knee osteoarthritis in order to understand the development of varus knee osteoarthritis. DESIGN Fifty-three patients (71 knees) with primary varus knee osteoarthritis and who underwent total knee arthroplasty were selected for this ...

Varus knee osteoarthritis: whence the varus?

With a biomechanical treatment in knee osteoarthritis, less knee pain did not correlate with synovitis reduction

BACKGROUND Braces are used to treat pain in patellofemoral joint osteoarthritis (PFJOA). In a trial, we previously reported pain improvement after 6-weeks brace use. The pain reduction did not correlate with changes in Magnetic Resonance Imaging (MRI) assessed Bone Marrow Lesion volume or static synovial volume. Studies show that changes in the synovium on dynamic contrast enhanced (DCE) MRI ar...

Cartilage markers in synovial fluid in symptomatic knee osteoarthritis.

OBJECTIVE To investigate if the relative content of aggrecan and cartilage oligomeric matrix protein (COMP) in synovial fluid lavage samples differs between individuals with knee pain with or without evidence of radiological knee osteoarthritis (joint space narrowing). METHODS In a community based cohort of 204 individuals aged 35-54 years with chronic (> 3 months duration) knee pain, a subgr...

Distal Femoral Varus Osteotomy for Lateral Compartment Osteoarthritis in the Valgus Knee. A Systematic Review of the Literature

The primary objectives of this systematic review were to define the indications, functional outcomes, survivorship and complications associated with distal femoral varus osteotomy (DFVO).Cumulative survival with arthroplasty as the endpoint ranged from 64 to 82% at 10 years, and 45% at 15 years. The mean pre-operative HSS score ranged from 46 to 65 and this improved at latest follow up to means...